Protein Purification Reagents and Kits
eMolecules 1256358-92-5 | Ambeed | 5-Bromo-2-(4455-tetramethyl-132-dioxaborolan-2-yl)-1H-indole | 250mg | 718339360 | A243568 | MFCD11858360 | 322.01 | C14H17BBrNO2
ChemScene | (R)-(66-Dimethylmorpholin-2-yl)methanol hydrochloride | 100mg | 569146498 | CS-0129999 | 1416444-88-6 | MFCD22690353 | 181.660 | C7H16ClNO2
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Genscript Corporation Her2/ErbB2Biotin His Avi
ErbB2 also called Neu and Her2 (human epidermal growth factor receptor 2) is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors Upon ERBB2 activation the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane
AdipoGen HpARI CCP1 2 rec His
Recombinant protein. Heligmosomoides polygyrus protein HpARI aa 17-165 is fused at the C-terminus to a His-tag. Binds to human and mouse IL-33. Endotoxin <0.01EU/µg purified protein LAL test. Lyophilized. Contains PBS. HpARI is a protein secreted by the mouse parasite Heligmosomoides polygyrus. The mature protein HpARI, containing three predicted Complement Control Protein CCP-like modules also known as Short Consensus Repeats SCRs or sushi-domains, suppresses type 2 allergic immune responses through interference in the interleukin-33 IL-33 pathway. During cell damage, HpARI gains access to the nucleus of necrotic cells, where it binds directly to IL-33 and nuclear DNA, preventing secretion and binding of IL-33 to its receptor. A non-natural truncation consisting of the first 2 domains of HpARI CCP1/2 retains IL-33 and DNA binding capacity. HpARI CCP1/2 is able to stabilize IL-33, increasing its half-life and amplifying its effects.
Genscript Corporation CD34 His Mouse
CD34 is a transmembrane phosphoglycoprotein first identified on hematopoietic stem and progenitor cells Clinically it is associated with the selection and enrichment of hematopoietic stem cells for bone marrow transplants Due to these historical and clinical associations CD34 expression is almost ubiquitously related to hematopoietic cells and it is a common misconception that CD34-positive (CD34()) cells in nonhematopoietic samples represent hematopoietic contamination
Antibodies Online TXNDC12 Protein (His tag) Recombinant Human Cells, This TXNDC12 protein is labelled with His tag. 50 μg
Background: Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain.
Genscript Corporation BCMA/TNFRSF17 His Cynomolgu
B-cell maturation antigen (BCMA or BCM) also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is a protein that in humans is encoded by the TNFRSF17 gene TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF)
Genscript Corporation MSLN/Mesothelin296-580 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
AdipoGen CD152 hrecHis
Recombinant Protein. Human CD152 aa 36-161 is fused at the C-terminus to a His-tag. Source W2. Lyophilized. Contains PBS. CD152 Cytotoxic T-lymphocyte-associated protein 4 CTLA-4 is an inhibitory receptor belonging to the CD28 immunoglobulin subfamily, expressed primarily by T-cells. Its ligands, CD80 and CD86, are typically found on the surface of antigen-presenting cells and can either bind CD28 or CTLA-4, resulting in a costimulatory or a co-inhibitory response, respectively. Because of its dampening effect, CTLA-4 is a crucial regulator of T-cell homeostasis and self-tolerance. While CD28 promotes T-cell activation and proliferation, CTLA-4 is reported to dampen T-cell responses through a variety of mechanisms. Prior to activation, conventional T-cells Tconv express low levels of CTLA-4, predominantly in intracellular compartments. Upon activation, CTLA-4 expression is upregulated and becomes increasingly detectable on the cell surface.
Genscript Corporation CD4/LEU3 His Mouse
CD4 also known as L3T4 T4 and W3/25 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes It is a standard phenotype marker for the identification of T cell populations Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses In T-cells functions primarily as a coreceptor for MHC class II molecule peptide complex
Genscript Corporation Her2 Avi His Human
ErbB2 also known as Neu and Her2 is a type I membrane glycoprotein belonging to the ErbB family of tyrosine kinase receptors It serves as a receptor for the epidermal growth factor (EGF) family of growth factors Upon activation ERBB2 triggers the MEMO1-RHOA-DIAPH1 signaling pathway leading to the phosphorylation and inhibition of GSK3B at the cell membrane
Genscript Corporation CD229/SLAMF3Biotin His Av
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS) smoldering myeloma MM and PC leukemia CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56 Most importantly CD229 was also highly expressed on those cells in the patients BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells
AdipoGen GPX1 human rec His
Protein. Human GPX1 aa 1-201 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. In PBS. Purity >90% SDS-PAGE. Glutathione peroxidase 1 GPX1 is an antioxidant enzyme that is down-regulated in cancer cells. Protects the hemoglobin in erythrocytes from oxidative breakdown. Its main role is the prevention of cancer initiation by ROS-mediated DNA damage.
AdipoGen Asprosin human rec His
Recombinant protein. Human asprosin aa 2732-2871 is fused at the C-terminus to a His-tag. Source E. coli. Lyophilized from 0.2µm-filtered solution in 50mM Tris-HClpH 8.2, 200mM NaCl. Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein pro-Fibrillin-1. Asprosin is secreted from white adipose tissue and increases hepatic glucose production by using cAMP as a second messenger, leading to activation of protein Kinase A. Reduction of Asprosin levels protects against metabolic syndrome-associated hyperinsulinism. Asprosin may act as a circulating hunger signal. Indeed, peripherally injected recombinant asprosin can cross the blood-brain barrier and intracerebroventricular i.c.v. injection of recombinant asprosin stimulated appetite in wild-type mice, indicating a central mechanism of action.
AdipoGen ACBP h rec His
Recombinant protein. Human acyl-CoA-binding protein aa 2-87 is fused at the C-terminus to a His-tag. Endotoxin <0.01EU/µg purified protein LAL test. Lyophilized. Contains PBS. Acyl-coenzyme A CoA-binding protein ACBP is an ubiquitously expressed 86 aa polypeptide that binds medium- and long-chain acyl-CoA esters with very high affinity. It plays a role as an intracellular carrier of acyl-CoA esters and regulates lipid metabolism in the cytoplasm of most cell types. In addition to its function within the cells as acyl-coenzyme A CoA-binding protein, ACBP also functions as secreted protein called Diazepam-Binding Inhibitor DBI that can interact with the benzodiazepine-binding site of the gamma-aminobutyric acid GABA type A receptor, GABAAR, and modulate its activity. ACBP is secreted upon induction of autophagy energy deficiency in different organisms including mouse and human. ACBP levels correlate with human body mass index BMI.
Genscript Corporation CD46 His Canine
CD46 was discovered in 1986 during a search for novel C3b-binding proteins CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated self-attack